Women's Health
CRINONE® 8% (progesterone gel)
CRINONE 4% (progesterone gel)
OTC Products
Men's Health

CRINONE 4%


CRINONE® 4% (progesterone gel) is a vaginal progesterone gel utilizing our sustained-release bioadhesive technology and indicated for the treatment of secondary amenorrhea. CRINONE was approved by the FDA in May 1997.

Columbia sold U.S. rights to CRINONE 4% to Watson Pharmaceuticals, Inc. in 2010. Merck Serono holds marketing rights for CRINONE 4% in all territories outside the United States, but does not actively market the product.

For more information, patient support, or to report an adverse event, please contact Watson Pharmaceuticals as follows:

  • Customer Support: 1-888-PROGEL8 (1-888-776-4358)
  • Medical Information: (800) 272-5525, option 2


CRINONE® is a registered trademarks of Watson Pharmaceuticals, Inc.